FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\Df(2L)BSC6
Open Close
General Information
Symbol
Df(2L)BSC6
Species
D. melanogaster
Name
FlyBase ID
FBab0029632
Feature type
chromosomal_deletion
Computed Breakpoints include
Features within 26D3--26F7
Genomic Maps
Sequence coordinates
2L:6,411,355..6,411,355 (Df(2L)BSC6:bk1)
(Cook, 2016.2.8)
2L:6,663,664..6,664,150 (Df(2L)BSC6:bk2)
(Cook, 2016.2.8)
Member of large scale dataset(s)
Dfs_BSC_set1

A set of ~50 targeted deficiencies created by exploiting hybrid element insertion (HEI) and resolution; designed to fill gaps in deletion coverage.

(Parks et al., 2004)
Nature of Aberration
Cytological Order
Progenitor
P{lacW}k09923
(Parks et al., 2004, Deal et al., 2001.8.1)
P{PZ}cup01355
(Parks et al., 2004, Deal et al., 2001.8.1)
Mutagen
Delta2-3 transposase
(Deal et al., 2001.8.1)
recombination
(Deal et al., 2001.8.1)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Parks et al., 2004, Deal et al., 2001.8.1)
Breakpoints

26D3-26E1;26F4-26F7

(Parks et al., 2004, Deal et al., 2001.8.1)
Causes alleles
Carries alleles
cn1
(Deal et al., 2001.8.1)
dpyov1
(Deal et al., 2001.8.1)
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments

The 2L:6411355 release 6 coordinate of the left breakpoint is an estimate. It corresponds to the insertion site of P{lacW}l(2)k09923k09923. As FBrf0175003 explains, deletions generated by P transposase in the presence of trans-heterozygous P elements are expected to extend from the end of one P insertion to the vicinity of the other P insertion. The absence of miniwhite from the Df(2L)BSC6 chromosome suggests that the deletion extends from the left end of the P{PZ}cup01355 insertion to the vicinity of P{lacW}l(2)k09923k09923.

(Cook, 2016.2.8)

The 2L:6663664..6664150 release 6 coordinate of the right breakpoint is an estimate. It corresponds to the insertion site of P{PZ}cup01355 in the 5' UTR of cup (FBrf0093133). As FBrf0175003 explains, deletions generated by P transposase in the presence of trans-heterozygous P elements are expected to extend from the end of one P insertion to the vicinity of the other P insertion. The absence of miniwhite from the Df(2L)BSC6 chromosome suggests that the deletion extends from the left end of the P{PZ}cup01355 insertion to the vicinity of P{lacW}l(2)k09923k09923.

(Cook, 2016.2.8)
Comments on Cytology
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Ent2
(Knight et al., 2010)
eya
(Deal et al., 2001.8.1)
mmy
(Tonning et al., 2006, Araujo et al., 2005)
Sec61α
(Wang and Ward, 2010)
Partially deleted / disrupted
Molecular Data
Completely deleted
mmy
(Shaik et al., 2011)
Trmt6
(Marygold et al., 2007)
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (43)
Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations

The Df(2L)BSC6 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion).

(Mason et al., 2004)
Stocks (2)
Notes on Origin
Discoverer
 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 

The miniwhite marker in the P{lacW} construct is disrupted or deleted in the Df(2L)BSC6 chromosome based on w- eye color in a w1 background.

(Deal et al., 2001.8.1)
Synonyms and Secondary IDs (2)
References (26)