FlyBase Aberration Report: Dmel\Df(3R)Cha7

General Information

Symbol

Df(3R)Cha7

Species

D. melanogaster

Name

Deficiency (3R) Choline Acetyltransferase

FlyBase ID

FBab0002512

Feature type

chromosomal_deletion

Also Known As

Df(3R)ChaM7, Df(3R)Cha^M7

Computed Breakpoints include

90F1-90F2;91F5

Features within 90F1--91F5

Sequence coordinates

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

Mutagen

gamma ray

(Gailey and Hall, 1989)

Class of aberration (relative to wild type)

chromosomal_deletion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Dickson et al., 1996, Ito et al., 1996, Harbecke and Lengyel, 1995, Pauli et al., 1995, Gailey et al., 1991, Gailey and Hall, 1989)

Breakpoints

90F;91F

(Dickson et al., 1996, Ito et al., 1996, Gailey et al., 1991, Gailey and Hall, 1989)

91A;91F5

(Harbecke and Lengyel, 1995)

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

sr << bk1 << repo << Cha << bk2 << cdi

Genetic mapping information

Comments

Comments on Cytology

Left limit of break 1 from polytene analysis (FBrf0049929) Right limit of break 1 from inclusion of repo (FBrf0072748) Limits of break 2 from polytene analysis (FBrf0082073)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

CG31224

(Thibault et al., 2004)

ChAT

(Gailey and Hall, 1989)

cona

(Page et al., 2007)

Dlc90F

(Caggese et al., 2001)

eIF1A

(Collins and Cohen, 2005)

fray

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

fru

(Gailey and Hall, 1989)

GatA

(Morris et al., 2008, Szeged Stock Center, 1998-)

(Gailey and Hall, 1989)

l(3)08126

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

l(3)S007302

(Szeged Stock Center, 1998-)

l(3)S024506

(Szeged Stock Center, 1998-)

l(3)S068609

(Szeged Stock Center, 1998-)

l(3)S074706

(Szeged Stock Center, 1998-)

l(3)S088501a

(Szeged Stock Center, 1998-)

l(3)S094603

(Szeged Stock Center, 1998-)

l(3)S098105

(Szeged Stock Center, 1998-)

l(3)S115909

(Szeged Stock Center, 1998-)

l(3)S125801b

(Szeged Stock Center, 1998-)

l(3)S148213

(Szeged Stock Center, 1998-)

repo

(Campbell et al., 1994)

sprd

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

VAChT

(Kitamoto et al., 2000)

Partially deleted / disrupted

Molecular Data

Completely deleted

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

cdi

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

cdm

(Giagtzoglou et al., 2009, Babcock et al., 2003)

Delta

(Alton et al., 1988)

Dlc90F

(BDGP Project Members, 1994-1999)

fsf

(Gailey and Hall, 1989)

l(3)91Fa

(Alton et al., 1988)

l(3)91Fb

(Alton et al., 1988)

l(3)91Fc

(Alton et al., 1988)

l(3)91Fe

(Alton et al., 1988)

l(3)91Ff

(Alton et al., 1988)

l(3)92Aa

(Alton et al., 1988)

l(3)neo49

(BDGP Project Members, 1994-1999)

l(3)neo50

(BDGP Project Members, 1994-1999)

l(3)S022930

(Szeged Stock Center, 1998-)

l(3)S042622

(Szeged Stock Center, 1998-)

l(3)S070103

(Szeged Stock Center, 1998-)

Mdh2

(Wang et al., 2008)

nanos

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

quag

(BDGP Project Members, 1994-1999)

S(CycE^JP)13S1

(Brumby et al., 2004)

sqz

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

(Gailey and Hall, 1989)

Ssdp

(BDGP Project Members, 1994-1999)

Xrp1

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (0)

If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
In these cases, there will be no "Export to Hitlist" button to the left.

Related Comments

Phenotypic Data

In combination with other aberrations

Inferred to overlap with: Df(3R)DG2.

(Carpenter, 2003.1.31)

Lethal in combination with Df(3R)fru^w24. Lethal in combination with Df(3R)fru^sat15. Lethal in combination with Df(3R)fru^4-40.

(Anand et al., 2001)

NOT in combination with other aberrations

The Df(3R)Cha7 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion).

(Mason et al., 2004)

Heterozygosity for Df(3R)Cha7 results in 1.1% X chromosome nondisjunction and 1.8% fourth chromosome nondisjunction in In(1)FM7/X ; sv^spa-pol females.

(Harris et al., 2003)

Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.

(Coyne et al., 1998)

No second site non-complementing phenotype with zip^Ebr and zip^mhc-c6.1.

(Halsell and Kiehart, 1998)

Shows no maternal enhancement of dpp^hr4.

(Nicholls and Gelbart, 1998)

Shows no phenotype when heterozygous with 14-3-3ε^18A2, and no effect on phl::tor^12D.hs.sev when heterozygous with wild type.

(Dickson et al., 1996)

Deficient embryos show an uninterpretable mutant midgut phenotype.

(Bilder and Scott, 1995)

Dorsal closure is abnormal in homozygous embryos, and tracheae do not fuse. The midgut epithelium does not completely surround the yolk and midgut constrictions are incomplete.

(Harbecke and Lengyel, 1995)

Df(3R)Cha7 exhibits a bisexual phenotype when in trans with a fru chromosome.

(Ito et al., 1995)

Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2.

(Pauli et al., 1995)

When heterozygous with fru, males are sterile and exhibit chain behaviour.

(Gailey and Hall, 1989)

Stocks (3)

Bloomington

3011

Df(3R)Cha7, red¹/TM6B, Tb¹

Kyoto

106780

Df(3R)Cha7/TM6B, Tb¹

103304

Df(3R)Cha7 / TM6B, Tb^*

Notes on Origin

Discoverer

Myers, Gelbart.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Stated that deletes or disrupts pont

(Szeged Stock Center, 1998-)

Synonyms and Secondary IDs (11)

Reported As

Symbol Synonym

Cha 7

(Misener et al., 2001)

Cha^M7

(Kitamoto et al., 2000)

DF(3R)Cha7

(Harris et al., 2003)

Df(3R)Cha

(Kimura et al., 2005)

Df(3R)Cha7

(Li et al., 2014, Rosenbaum et al., 2014, Ghabrial et al., 2011, Wright et al., 2010, Giagtzoglou et al., 2009, Bejarano et al., 2008, Wang et al., 2008, Page et al., 2007, Liao et al., 2006, Tselykh et al., 2005)

Df(3R)Cha^M7

(Anand et al., 2001, Ito et al., 1996, Ito et al., 1995, Gailey et al., 1991, Gailey and Hall, 1989, Alton et al., 1988)

Df(3R)ChaM7

(Firth et al., 2000, Carrera et al., 1998, Bilder and Scott, 1995, Harbecke and Lengyel, 1995, Pauli et al., 1995, Smith et al., 1993)

Df(3R)Cham7

(Campbell et al., 1994)

Df(3R)cha7

(Guichet et al., 2002)

Df(3R)cha⁷

(Morris et al., 2008)

Name Synonyms

Deficiency (3R) Choline Acetyltransferase

Secondary FlyBase IDs

References (61)

Report Sections

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