FlyBase Aberration Report: Dmel\Df(2L)cl-h3

General Information

Symbol

Df(2L)cl-h3

Species

D. melanogaster

Name

Deficiency (2L) clot

FlyBase ID

FBab0001758

Feature type

chromosomal_deletion

Also Known As

Df(2L)cl^h3, Df(2L)c1-h3

Computed Breakpoints include

25D2-25D3;26B2-26B5

Features within 25D2--26B5

Sequence coordinates

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

Mutagen

X ray

Class of aberration (relative to wild type)

chromosomal_deletion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Harbecke and Lengyel, 1995, Pauli et al., 1995, Nellen et al., 1994, Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)

Breakpoints

25D2-25D4;26B2-26B5

(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)

25D2-25D4;25F1-25F2

(Harbecke and Lengyel, 1995, Pauli et al., 1995, Nellen et al., 1994)

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

Msp-300 << bk1 << tkv << chic << bk2 << Su(var)25F26B

Genetic mapping information

Comments

Comments on Cytology

Left limit of break 1 from polytene analysis (FBrf0047784) Right limit of break 1 from polytene analysis (citation unavailable) Limits of break 2 from polytene analysis (FBrf0047784)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

chic

(Wills et al., 1999, van Vactor et al., 1993)

(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988, Kotarski et al., 1983)

E(var)25F

(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)

eIF4A

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Hel25E

(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988, Kotarski et al., 1983)

Kdm5

(Gildea et al., 2000)

l(2)25Ea

(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)

l(2)25Ed

(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)

l(2)25Ee

(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)

l(2)25Ef

(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)

l(2)25Fa

(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)

l(2)k06502

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

l(2)k07109a

(BDGP Project Members, 1994-1999)

Lam

(Guillemin et al., 2001, Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)

mid

(Harbecke and Lengyel, 1995, Szidonya and Reuter, 1988, Szidonya and Reuter, 1988, Kotarski et al., 1983)

nompC

(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)

slmo

(Carhan et al., 2004)

tkv

(Spradling et al., 1999, Harbecke and Lengyel, 1995, BDGP Project Members, 1994-1999, Nellen et al., 1994)

vri

(Blau and Young, 1999, Spradling et al., 1999, BDGP Project Members, 1994-1999)

Partially deleted / disrupted

Molecular Data

Completely deleted

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

Col4a1

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

eIF3h

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Kr-h1

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

l(2)25Ca

(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)

l(2)25Cc

(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)

l(2)25Cd

(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)

l(2)25Ce

(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)

l(2)25Cf

(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)

l(2)25Cg

(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)

l(2)04884

(BDGP Project Members, 1994-1999)

l(2)k04909b

(BDGP Project Members, 1994-1999)

Msp300

(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)

RpL37A

(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)

Su(var)25F26B

(Wustmann et al., 1989)

thr

(Liu et al., 1999)

tkv

(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)

vkg

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

vri

(Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (0)

If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
In these cases, there will be no "Export to Hitlist" button to the left.

Related Comments

Phenotypic Data

In combination with other aberrations

The penetrance of the extra sex comb teeth phenotype seen in Df(3L)Pc flies is suppressed by Df(2L)cl-h3.

(Gildea et al., 2000)

Effect on variegation of y in In(1)y^3P and Sb in T(2;3)Sb^V studied: inactivation of y occurs independently of inactivation of Sb.

(Bishop, 1992)

Enhancer of In(1)w^m4h position-effect variegation.

(Wustmann et al., 1989)

NOT in combination with other aberrations

The Df(2L)cl-h3 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion).

(Mason et al., 2004)

The period length of the locomotor activity rhythm is significantly shorter in heterozygotes than in wild-type flies.

(Blau and Young, 1999)

Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.

(Coyne et al., 1998)

Intermediate second site non-complementing phenotype with zip^Ebr and zip^mhc-c6.1 : malformed phenotype penetrance 25-75%.

(Halsell and Kiehart, 1998)

Shows no maternal enhancement of dpp^hr4.

(Nicholls and Gelbart, 1998)

Midgut development of mutant embryos is wild type.

(Bilder and Scott, 1995)

Homozygous embryos have abnormal tracheae and dorsal closure is abnormal.

(Harbecke and Lengyel, 1995)

Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2.

(Pauli et al., 1995)

Suppresses In(1)w^m4h position-effect variegation.

(Szidonya and Reuter, 1988)

Stocks (2)

781

108918

Notes on Origin

Discoverer

Isolated over Dp(2;2)B3 = Dp(2;2)23E2-3;26E2-F1

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms and Secondary IDs (8)

Reported As

Symbol Synonym

Df(2L)-cl(h3)

(Blau and Young, 1999)

Df(2L)c1-h3

(LaJeunesse et al., 2001, Spradling et al., 1999, Halsell and Kiehart, 1998)

Df(2L)ch-h3

(Bilder and Scott, 1995)

Df(2L)cl-h3

(Clough et al., 2014, Galindo et al., 2014, Fernandes and Rao, 2011, Ida et al., 2009, Crest et al., 2007, Jiang et al., 2007, Secombe et al., 2007)

Df(2L)cl^h3

(Abrell et al., 2000, Wills et al., 1999, van Vactor et al., 1993, Wustmann et al., 1989, Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)

E(brm^K804R)25D-26D

(Brumby et al., 2002)

cl-h3

(Hirose et al., 2001)

Name Synonyms

Deficiency (2L) clot

Secondary FlyBase IDs

References (52)

Report Sections

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