FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\Df(1)KA6
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General Information
Symbol
Df(1)KA6
Species
D. melanogaster
Name
FlyBase ID
FBab0000484
Feature type
chromosomal_deletion
Computed Breakpoints include

10E1;11A7

Features within 10E1--11A7
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
X ray
(Eeken and Sobels, 1990)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Duffy et al., 1996, Pauli et al., 1995, Anand and Chandra, 1994, Konopka et al., 1991, Rodrigues et al., 1991, Eeken and Sobels, 1990, Arora et al., 1987, Bolshakov and Zhimulev, 1987, Mason et al., 1981, Craymer and Roy, 1980)
Breakpoints

10E1;11A7

(Rodrigues et al., 1991, Eeken and Sobels, 1990, Arora et al., 1987, Craymer and Roy, 1980)

10E2;11A7

(Mason et al., 1981)

10E1-10E2;11A6-11A9

(Bolshakov and Zhimulev, 1987)

10E1;11A7-11A8

(Duffy et al., 1996, Pauli et al., 1995, Anand and Chandra, 1994, Konopka et al., 1991)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

Rst(1)JH << bk1 << l(1)10Fk << l(1)10Ea << bk2 << gs(1)N41

Genetic mapping information
Comments

Breakpoint(s) molecularly mapped

(Jackson, 1990)
Comments on Cytology

Deletion of 22/24 bands.

(Eeken and Sobels, 1990)

All limits from polytene analysis (FBrf0034402)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations

    Df(1)KA6/Df(1)m259-4 heterozygotes are viable.

    (Rodrigues et al., 1991)

    Heterozygotes with Df(1)m259-4 survive and have an extreme m phenotype with flimsy wings.

    (Craymer and Roy, 1980)
    NOT in combination with other aberrations

    Df(1)KA6 hemizygous embryos exhibit head and thorax defects similar to tsg loss of function mutants.

    With a very low penetrance, Df(1)KA6 hemizygous embryos show subtle defects in segmentation, including partial fusion of denticle band pairs in the register seen for Ten-m mutants.

    Flies with transheterozygous combinations of Df(1)KA6/+ and Ten-m628/+ display eye roughness. Consistent features include ommatidial order defects, ommatidial fusions, eye sensory bristle loss, and occasional supernumerary sensory bristles.

    (Rakovitsky et al., 2007)

    Hemizygous late embryonic lethal.

    (Franke and Baker, 1999)

    Acts as a dosage sensitive maternal modifier of run : causes tergite defects in greater than 50% of run3 heterozygotes. Maternal heterozygosity for Df(1)KA6 greatly increases the frequency of segmentation defects in embryos heterozygous for eve, run and Kr.

    (Duffy et al., 1996)

    Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.

    (Pauli et al., 1995)

    No significant change in female lethality when in combination with Sxlf1.

    (Anand and Chandra, 1994)

    Heterozygous females exhibit reduced viability and fertility.

    (Eeken and Sobels, 1990)
    Stocks (2)
    Notes on Origin
    Discoverer

    Lefevre.

     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (3)
    Reported As
    Symbol Synonym
    Df(1)KA6
    (Kinel-Tahan et al., 2007, Rakovitsky et al., 2007, Savvateeva-Popova et al., 2004)
    DfKA6
    (Mason et al., 1981)
    KA-6
    (Sanchez et al., 1994)
    Name Synonyms
    Secondary FlyBase IDs
      References (30)