Vertex Pharmaceuticals Incorporated (VRTX)
News headlines Vertex Pharmaceuticals is navigating a challenging landscape marked by setbacks in its pain management program and recent licensing agreements. Despite these hurdles, upcoming earnings reports and analyst upgrades may provide insights into its future performance.
Vertex Pharmaceuticals is navigating a challenging landscape marked by setbacks in its pain management program and recent licensing agreements. Despite these hurdles, upcoming earnings reports and analyst upgrades may provide insights into its future performance.
- Previous Close
469.90 - Open
465.65 - Bid 469.51 x 100
- Ask 470.38 x 100
- Day's Range
464.01 - 473.74 - 52 Week Range
362.50 - 519.68 - Volume
759,623 - Avg. Volume
1,421,806 - Market Cap (intraday)
121.019B - Beta (5Y Monthly) 0.32
- PE Ratio (TTM)
33.22 - EPS (TTM)
14.21 - Earnings Date Feb 12, 2026
- Forward Dividend & Yield --
- Ex-Dividend Date --
- 1y Target Est
514.32
Vertex Pharmaceuticals Incorporated, a biotechnology company, engages in developing and commercializing therapies for treating cystic fibrosis (CF). It markets TRIKAFTA/KAFTRIO for people with CF with at least one F508del mutation for 2 years of age and older; ALYFTREK for the treatment for people with CF 6 years of age and older; SYMDEKO/SYMKEVI for treatment of patients with CF 6 years of age and older; ORKAMBI for CF patients 1 year or older; and KALYDECO for the treatment of patients with 1 month or older who have CF with ivacaftor. The company also develops CASGEVY for the treatment of sickle cell disease and transfusion-dependent beta thalassemia; JOURNAVX for the treatment of acute pain in adults; VX-522, a CFTR mRNA therapeutic designed to treat the underlying cause of CF, which is in Phase 1/2 clinical trial; inaxaplin for the treatment of APOL1-mediated kidney disease which is in single Phase 2; VX-880 and VX-264, treatment for Type 1 Diabetes; VX-670 for the treatment of myotonic dystrophy type 1; and VX-407, a small molecule corrector for the treatment of autosomal dominant polycystic kidney disease. Further, it sells the products to specialty pharmacy and specialty distributors in the United States, as well as retail pharmacies, hospitals, and clinics. Additionally, the company has collaborations with CRISPR Therapeutics AG.; Moderna, Inc.; and Entrada Therapeutics, Inc. Vertex Pharmaceuticals Incorporated was founded in 1989 and is headquartered in Boston, Massachusetts.
www.vrtx.comRecent News: VRTX
View MorePerformance Overview: VRTX
Trailing total returns as of 2/2/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC) .
YTD Return
1-Year Return
3-Year Return
5-Year Return
Earnings Trends: VRTX
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View MoreValuation Measures
Market Cap
120.69B
Enterprise Value
116.24B
Trailing P/E
33.07
Forward P/E
24.04
PEG Ratio (5yr expected)
--
Price/Sales (ttm)
10.35
Price/Book (mrq)
6.88
Enterprise Value/Revenue
9.79
Enterprise Value/EBITDA
24.62
Financial Highlights
Profitability and Income Statement
Profit Margin
31.35%
Return on Assets (ttm)
12.04%
Return on Equity (ttm)
22.31%
Revenue (ttm)
11.72B
Net Income Avi to Common (ttm)
3.68B
Diluted EPS (ttm)
14.21
Balance Sheet and Cash Flow
Total Cash (mrq)
6.29B
Total Debt/Equity (mrq)
10.59%
Levered Free Cash Flow (ttm)
2.91B
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Research Reports: VRTX
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Newly launched Alyftrek approaches blockbuster status
Vertex Pharmaceuticals develops therapies to address cystic fibrosis and other diseases. The company was founded in 1989 in Cambridge, Massachusetts and has 6,100 employees. It has research programs and facilities in the U.S., the U.K., and Canada. The shares are a component of the S&P 500.
RatingPrice TargetVertex Earnings: Trikafta Drives Solid Growth, but Slow Sales From Other Products in Portfolio
Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio, and Alyftrek for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex has diversified its portfolio through Casgevy, a gene-editing therapy for beta thalassemia and sickle-cell disease, and Journavx, a non-opioid pain medication approved for the treatment of moderate-to-severe acute pain in adults. Additionally, Vertex is evaluating small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
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